个人简介：
董晓燕
教授，工学博士（天津大学），博导
d_xy@tju.edu.cn
研究方向包括：蛋白质聚集及其抑制和生物催化等基础和应用基础研究。
研究领域：
1. 蛋白质聚集及抑制：针对阿尔兹海默症开展蛋白质聚集及其抑制理论和抑制剂设计的研究。
2. 生物催化：酶分子工程、酶修饰和固定化与多酶组装及其级联反应的设计。
学术成就：
先后主持并完成国家自然科学基金、天津市自然科学重点基金、天津市自然科学基金、教育部归国留学资助基金和教育部优秀青年教师基金等12项科研资助项目。主要研究成果在国内外学术刊物发表论文200余篇。其中SCI 、EI收录论文近180余篇。参加申请国家发明专利40余项，获国家发明专利20余项。已完成并参与完成国家自然科学基金、国家教委跨世纪优秀人才培养计划基金、国家杰出青年基金、国家重点发展计划973和863等研究课题30余项。已培养博士生16人，硕士生47人。
代表性文章：
1. Luqi Liu, Wei Liu*, Yan Sun, Xiaoyan Dong*: Serum albumin-embedding copper nanoclusters inhibit Alzheimer’s β-amyloid fibrillogenesis and neuroinflammation. Journal of Colloid and Interface Science, 2024, 72: 53-62.
2. Zitong Wei, Xiaoyan Dong*, Yan Sun*: Quercetin-derived red emission carbon dots: A multifunctional theranostic nano-agent against Alzheimer's β-amyloid fibrillogenesis. Colloids and Surfaces B: Biointerfaces, 2024, 238: 113907
3. Ying Wang, Wei Liu*, Yan Sun, Xiaoyan Dong*: Transthyretin-penetratin: A potent fusion protein inhibitor against Alzheimer’s amyloid-β fibrillogenesis with high blood brain barrier crossing capability. Bioconjugate Chemistry, 2024, 35 (3): 419–431.
4. Weiqun Gao, Wei Liu, Xiaoyan Dong*, Yan Sun*: Albumin-manganese dioxide nanocomposite: A potent inhibitor and ROS scavenger against Alzheimer's β-amyloid fibrillogenesis and neuroinflammation. Journal of Materials Chemistry B, 2023
5. Luqi Liu, Wei Liu, Yan Sun, Xiaoyan Dong*: Design of aggregation-induced emission-active fluorogen-based nanoparticles for imaging and scavenging Alzheimer's β-amyloid by photo-oxygenation. Journal of Materials Chemistry B, 2023,11: 8994-9004.
6. Ying Wang, Wei Liu, Xiaoyan Dong*, Yan Sun: Design of self-assembled nanoparticles as a potent inhibitor and fluorescent probe for β-amyloid fibrillogenesis. Langmuir, 2023, 39 (36): 12576-12589
7. Zhenfu Wang#, Jie Gao#, Qinghong Shi#, Xiaoyan Dong*, Yan Sun: Facile purification and immobilization of organophosphorus hydrolase on protein-inorganic hybrid phosphate nanosheets. Chinese Journal of Chemical Engineering, 2023, 56:119-125.
8. Xueqing Chen, Weiqun Gao, Yan Sun, Xiaoyan Dong*: Multiple effects of polydopamine nanoparticles on Cu2+-mediated Alzheimer's β-amyloid aggregation. Chinese Journal of Chemical Engineering, 2023, 54: 144-152
9. Miaomiao Liu, Wenjuan Wang, Xaoping Hao, Xiaoyan Dong*: Seeding and Cross-seeding Aggregations of Aβ40 and hIAPP in Solution and on Surface. Acta Physico-Chimica Sinica, 2022, 38 (3): 2002024.
10. Chunyu Zhang, Yan Sun, Xiaoyan Dong*: Conjugation of a zwitterionic polymer with dimethyl chains to lipase significantly increases the enzyme activity and stability. Chinese Journal of Chemical Engineering, 2022, 47, 48−53
