财音青格乐，蒙古族，副教授，博士生导师

qinggele@tju.edu.cn

个人介绍：理学博士，毕业于南开大学生命科学学院微生物学专业。

研究领域

主要研究方向为微生物合成生物学、微生物人工细胞工厂设计与改造、肠道微生物与营养健康研究。

学术成就

荣誉奖项、科研项目（主持的重要项目）、专利等。

主持完成2项国家自然科学基金项目、1项“863”子课题项目、1项国家重点研发项目子课题和1项天津市自然科学基金项目，参与多项国家自然科学基金项目、科技部重点研发项目和省部级科研项目。

代表性文章

2026年1月份为止，已发表高水平论文50余篇，其中代表性文章如下：

1 Wu S, Bu X, Chen D, Wu X, Wu H, Caiyin Q, Qiao J. Molecules-mediated bidirectional interactions between microbes and human cells. NPJ Biofilms Microbiomes. 2025 Mar 4;11(1):38. doi: 10.1038/s41522-025-00657-2. PMID: 40038292; PMCID: PMC11880406.

2 Lu J, Wu H, Wu S, Wang S, Fan H, Ruan H, Qiao J, Caiyin Q, Wen M. Salmonella: Infection mechanism and control strategies. Microbiol Res. 2025 Mar;292:128013. doi: 10.1016/j.micres.2024.128013. Epub 2024 Dec 12. PMID: 39675139.

3 Chen C, Zhang Y, Chen R, Liu K, Wu H, Qiao J, Caiyin Q. Development of a Pre-Modification Strategy to Overcome Restriction-Modification Barriers and Enhance Genetic Engineering in Lactococcus lactis for Nisin Biosynthesis. Int J Mol Sci. 2025 Feb 28;26(5):2200. doi: 10.3390/ijms26052200. PMID: 40076820; PMCID: PMC11900431.

4 Hu L, Lu J, Fan H, Niu C, Han Y, Caiyin Q, Wu H, Qiao J. FAS mediates apoptosis, inflammation, and treatment of pathogen infection. Front Cell Infect Microbiol. 2025 Apr 22;15:1561102. doi: 10.3389/fcimb.2025.1561102. PMID: 40330016; PMCID: PMC12052831.

5 Chen C, Zhang Y, Wu H, Qiao J, Caiyin Q. Advances in Diversity, Evolutionary Dynamics and Biotechnological Potential of Restriction-Modification Systems. Microorganisms. 2025 May 14;13(5):1126. doi: 10.3390/microorganisms13051126. PMID: 40431298; PMCID: PMC12114051.

6 Wang S, Zhou J, Zhan C, Qiao J, Caiyin Q, Huang M. Fine-Tuning the Function of Farnesene Synthases for Selective Synthesis of Farnesene Stereoisomers. J Agric Food Chem. 2024 Dec 11;72(49):27355-27364. doi: 10.1021/acs.jafc.4c09515. Epub 2024 Nov 26. PMID: 39588907; PMCID: PMC11638952.

7 Wu S, Qu Z, Chen D, Wu H, Caiyin Q, Qiao J. Deciphering and designing microbial communities by genome-scale metabolic modelling. Comput Struct Biotechnol J. 2024 Apr 22;23:1990-2000. doi: 10.1016/j.csbj.2024.04.055. PMID: 38765607; PMCID: PMC11098673.

8 E Y, Li W, Guo H, Zhang X, Caiyin Q, Yuan Y. Dynamic profiling of metabolite changes and health-promoting functions in 'yuling paste' during nine steaming and nine sun-drying processes. Food Chem X. 2024 Jul 18;23:101668. doi: 10.1016/j.fochx.2024.101668. PMID: 39139487; PMCID: PMC11321412.

9 Yan X, David SD, Du G, Li W, Liang D, Nie S, Ge M, Wang C, Qiao J, Li Y, Caiyin Q. Biological Properties of Sandalwood Oil and Microbial Synthesis of Its Major Sesquiterpenoids. Biomolecules. 2024 Aug 8;14(8):971. doi: 10.3390/biom14080971. PMID: 39199359; PMCID: PMC11352278.

10 Wang S, Zhan C, Nie S, Tian D, Lu J, Wen M, Qiao J, Zhu H, Caiyin Q. Enzyme and Metabolic Engineering Strategies for Biosynthesis of α-Farnesene in Saccharomyces cerevisiae. J Agric Food Chem. 2023 Aug 23;71(33):12452-12461. doi: 10.1021/acs.jafc.3c03677. Epub 2023 Aug 13. PMID: 37574876.