个人简介

姓名：赵志敏

职称：副研究员

电子邮箱：rzmzhao@tju.edu.cn

研究方向：合成生物制造、生物炼制、木质素高值化

赵志敏，博士生导师，先后获北京理工大学制药工程学士、中国科学院大学生物化工博士学位。曾在美国橡树岭国家实验室、田纳西大学从事博士后研究。

研究领域

从事合成生物学及绿色生物制造研究，在木质素生物转化、生物质炼制、发酵过程强化等领域取得系列创新成果。面向自然界来源广泛且可再生的木质纤维素生物质，通过绿色生物技术（包括系统与合成生物学，微生物代谢强化等），提升生物质可利用性，高效生产纤维素乙醇、油脂、微生态制剂等产品，以缓解能源与环境危机，推动抗生素绿色替代，助力实现“双碳” 战略目标。

学术成就

在Biotechnology Advances、Matter、Green Chemistry、Bioresoure Technology、ACS Sustainable Chemistry & Engineering等期刊发表SCI论文30余篇，参编“十四五”规划教材及英文学术专著6部，授权/申请专利6项。担任Resources Chemicals and Materials（ESCI, EI）、生物工程学报（EI）首届青年编委。主持国家重点研发计划“合成生物学”重点专项课题、国家自然科学基金等国家及省部级科研项目（课题）10余项。研究成果获中国石油和化学工业联合会科技进步奖1项，两次入选美国能源部生物能源创新中心研究亮点。

代表性文章

1. Zhi-Min Zhao^#, Zhi-Hua Liu^#, Tongtong Zhang, Rongqian Meng, Zhiqun Gong, Yibing Li, Jing Hu, Arthur J. Ragauskas*, Bing-Zhi Li*, Ying-Jin Yuan. Unleashing the capacity of Rhodococcus for converting lignin into lipids. Biotechnology Advances, 2024, 70, 108274.

2. Zhi-Min Zhao, Shuyang Zhang, Xianzhi Meng, Yunqiao Pu, Zhi-Hua Liu, William K. Ledford, S. Michael Kilbey II, Bing-Zhi Li, Arthur J. Ragauskas*. Elucidating the mechanisms of enhanced lignin bioconversion by an alkali sterilization strategy. Green Chemistry, 2021, 23, 4697-4709. (Cover Story, Research Highlight of CBI, U.S. DOE)

3. Zhi-Min Zhao, Xianzhi Meng, Brent Scheidemantle, Yunqiao Pu, Zhi-Hua Liu, Bing-Zhi Li, Charles E. Wyman, Charles M. Cai, Arthur J. Ragauskas*. Co-solvent enhanced lignocellulosic fractionation tailoring lignin chemistry and enhancing lignin bioconversion. Bioresource Technology, 2022, 347, 126367.

4. Zhi-Min Zhao, Xianzhi Meng, Manjula Senanayake, Sai Venkatesh Pingali, Yunqiao Pu, Mi Li, Litong Ma, Jifei Xu, Arthur J. Ragauskas*. Enhancing lignin dispersion and bioconversion by eliminating thermal sterilization. ACS Sustainable Chemistry & Engineering, 2022, 10, 3245-3254.

5. Zhi-Min Zhao, Xianzhi Meng, Yunqiao Pu*, Mi Li, Yibing Li, Yihan Zhang, Arthur J. Ragauskas*. Bioconversion of homogeneous linear C-lignin to polyhydroxyalkanoates. Biomacromolecules, 2023, 24, 9, 3996-4004.

6. Zhi-Min Zhao, Zhi-Hua Liu, Yunqiao Pu, Xianzhi Meng, Jifei Xu, Joshua S. Yuan, Arthur J. Ragauskas*. Emerging strategies for modifying lignin chemistry to enhance biological lignin valorization. ChemSusChem, 2020, 13, 5423-5432.

7. Chonglei Li, Zhiguo Liu, Zhiqun Gong, Zhihua Bao, Ji Zhao, Zhi-Min Zhao*. Steam explosion enhancing Bacillus subtilis fermentation on lignocellulosic biomass to prepare high-titer microecological agents. Industrial Crops and Products, 2025, 226, 120707.

8. Chonglei Li, Zhiguo Liu, Ji Zhao, Zhi-Min Zhao*. Mechanisms and strategies for regulating sporulation and germination of Bacillus subtilis to enhance probiotic effects. Industrial Crops and Products, 2024, 220, 119178.

9. Tongtong Zhang, Ziyi Zhao, Tao Xu, Zhihua Bao, Zhi-Hua Liu, Arthur J. Ragauskas, Zhi-Min Zhao*, Bing-Zhi Li. Lignin molecular modification enhancing its bioaccessibility and biotransformation. Journal of Agricultural and Food Chemistry, 2025, 73, 30429−30443

10. Rongqian Meng^#, Siying Zhang^#, Yihan Zhang, Ziyi Zhao, Zhihua Bao, Zhi-Hua Liu, Zhi-Min Zhao*, Bing-Zhi Li. Lignin fractionation coupling laccase-mediated depolymerization enhancing biological lignin valorization. Journal of Agricultural and Food Chemistry, 2025, 73, 14479-14492.